product

Estradiol valerate CAS: 979-32-8

Short Description:

Megestrol is an orally active progestogen. Megestrol is used in combinations as oral contraceptive and as antineoplastic agent.


Product Detail

FAQ

Product Tags

Description

Estradiol valerate (EV, E2V) (INN, USAN, JAN) (brand names Altadiol, Deladiol, Delestrogen, Estraval, Lastrogen, Progynova, Valergen, many others), or oestradiol valerate (BAN), is a synthetic ester, specifically the 17-pentanoyl ester, of the natural estrogen, 17β-estradiol. It was first introduced, as Delestrogen by Squibb in the United States, in 1954, and along with estradiol benzoate (1936) and estradiol cypionate (1952), has since become one of the most widely used esters of estradiol.
Upon ingestion, regardless of the route of administration, estradiol valerate behaves as a prodrug, being cleaved by esterases in blood plasma and the liver into 17β-estradiol and valeric acid. However, compared to estradiol itself, estradiol valerate is absorbed more slowly and possesses a longer duration, especially when given in an oil solution via intramuscular injection (in which it acts as a depot). As a result, it can be administered less frequently.
A single intramuscular injection of 4mg estradiol valerate results in maximal plasma levels of estradiol of about 390 pg/mL within three days of administration, with levels declining to 100 pg/mL by 12–13 days. A study of high-dose combined administration of 40mg estradiol valerate and 250mg hydroxyprogesterone caproate in women once weekly for six months (described as a “pseudopregnancy” regimen) found that serum levels of estradiol increased from 27.8–34.8 pg/mL to 3028–3226 pg/mL after three months and to 2491–2552 pg/mL after six months of treatment.

Basic Info

Chemical Name Estradiol 17-Valerate
Synonyms Estradiol valerate;
CAS No. 979-32-8
Molecular Formula C23H32O3
Molecular Weight 356.49800
PSA 46.53000
LogP 5.35030

Numbering system

UNII OKG364O896

Properties

Appearance & Physical State Na
Density 1.13g/cm3
Boiling Point 486.2ºC at 760mmHg
Melting Point 144ºC
Flash Point 191.1ºC
Refractive Index 1.567

Safety Info

RTECS KG5793000
Safety Statements S53-S45
WGK Germany 3
Risk Statements R60; R61
Hazard Codes T

Contact Us
wechat/whatsapp +8613081092107
skype/e-mail julia@hbshuoxi.com

 

Product Style

_MG_4750

 

Popular products

100-09-4 4-methoxybenzoic acid 23076-35-9 Xylazine hydrochloride
138-59-0 Shikimic acid 56786-63-1 5A-Hydroxy Laxogenin
1451-83-8 2-Bromo-4-Methylpropi 103-81-1 2-phenylacetamide
6080-56-4 lead diacetate trihydrate 131707-25-0 Arbidol
62-44-2 phenacetn 137-58-6 lidocaine
94-09-7 benzocaine 148553-50-8 pregabalin
94-15-5 Dimethocaine 16595-80-5 Levamisole hcl
136-47-0 Tetracaine hydrochloride 81646-13-1 Btms
23239-88-5 Benzocaine Hydrochloride 78-67-1 AIBN-64
593-51-1 methylamine hydrochloride 94-24-6 Tetracaine
73-78-9 lidocaine hydrochloride 2893-78-9 SDIC
99-92-3 4-Aminoacetophenone 4584-49-0 2-Dimethylaminoisopropyl Chloride
41979-39-9 4-oxopiperidinium chloride 49851-31-2 α-Bromovalerophenone
40064-34-4 4-Piperidon 5337-93-9 4-methylpropiophenone
705-60-2 Phenyl-2-nitropropene 459-03-0 4-Fluorophenylacetone
37148-47-3 4-Amino-3,5-dichlorophenacylbromide 49851-31-2 2-Bromo-1-phenyl-1-pentanone
37148-48-4 4-Amino-3,5-dichloroacetophenone 600-00-0 Ethyl 2-Bromoisobutyrate
23426-63-3 methyl 2-bromo-2-methylpropanoate 5445-19-2 Methyl 2-Bromohexanoate
64-17-5 Ethanol 100-07-2 4-Methoxybenzoyl chloride
96-48-0 γ-Butyrolactone 103-63-9 (2-Bromoethyl)benzene
9003-01-4 Polyacrylic acid 9007-20-9 Carbomer
54182-57-9 Carbopol (8CI)    

 

Company Products And Packaging

gfhdfh (1) 
Thanks for your considering of Hebei Shuoxi Biotechnology Co., Ltd.(HBSX).   HBSX is a fast growing intermediates company,Which located in Shijiazhuang,Hebei Province.
HBSX is specialized in pharmaceutical intermediates, veterinary drug intermediates and dyes intermediates,such as phenylacetamide, dimethylamine hcl, benzyl chloride etc., HBSX also supply various industrial chemicals for customers, such as citric acid,potassium chloride etc.
After ten years development,HBSX has become a Diversified development company,not only involves in chemicals, but also real estate ,clothes ,agricultural products and so on.
So far, HBSX has business in more than 35 countries,most big customers come from europe and America, because among the suppliers in china,HBSX can always make the product quality best, some of the products from HBSX can reach the purity of 99.9+, such as 2-phenylacetamide. This is the important reason for customers who choosing HBSX.
In future, HBSX must become to a more important trade bridge for china and foreign countries especially in pharmaceutical industries.

 

Packing

gfhdfh (2)

 

Why Choose US?
1. Selecting raw materials strictly,our products are the highest purity.
2.Reasonable and competitive price. Provide the best and professional service.
3.Fast delivery of the samples ,samples from stock. Reliable shipping way.
4.Full experience of large numbers containers loading in Chinese sea port.
5. Best after-service after shipment .
6. Professional documents for your custom clearance.

 

FAQ:
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.

Q2:What’s your MOQ?
A: For the high value product, our MOQ starts from 10g,100g and 1kg.

Q3:Which kind of payment terms do you accept?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment
by T/T, Western Union or Alibaba). Bulk order by T/T or L/C.

Q4:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.

Q5:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.


  • Previous:
  • Next:

  • Write your message here and send it to us