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Ethynyl estradiol CAS: 57-63-6

Short Description:

Megestrol is an orally active progestogen. Megestrol is used in combinations as oral contraceptive and as antineoplastic agent.


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 Description

Ethinyl estradiol, also sometimes written as 17α-ethinyl estradiol, ethinylestradiol, ethynyl estradiol, or ethinyl œstradiol, is a derivative of 17β-estradiol (E2), the major endogenous estrogen in humans. EE2 is an orally bioactive estrogen used in many formulations of combined oral contraceptive pills and is one of the most commonly used medications for this purpose.
Transdermal ethinyl estradiol carries a greater risk of clot formation and venous thromboembolism than naturally occurring 17β-estradiol, which some have theorized to be related to different amounts of hepatic metabolism after absorption. The same contraindications and precautions apply for EE2 as with other estrogen medications.
Estinyl was a preparation of EE2 alone that was used for the management of menopausal symptoms and female hypogonadism.
EE2 is released into the environment as a xenoestrogen from the urine and feces of people who take it as a medication.
The major concern with unopposed estrogen (without progestogen) is of endometrial cancer. As such, the medication is generally prescribed with progesterone in the setting of birth control.

Basic Info

Chemical Name 17α-ethynylestradiol
Synonyms Ethynylestradiol;17alpha-ethynylestradiol;LYNORAL;19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17α)-;Ethinyl Estradiol;Expand
CAS No. 57-63-6
Molecular Formula C20H24O2
Molecular Weight 296.40300
PSA 40.46000
LogP 3.61260

Numbering system

UNII 423D2T571U

Properties

Appearance & Physical State Off-White to Light-Yellow Crystalline Powder
Density 1.21g/cm3
Boiling Point 457.2ºC at 760mmHg
Melting Point 182-183ºC
Flash Point 211.2ºC
Refractive Index -30 ° (C=0.4, Pyridine)
Storage Condition Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Safety Info

RTECS RC8925000
Safety Statements S53-S36/37/39-S45
HS Code 2937290090
WGK Germany 3
Risk Statements R45; R22
Hazard Codes T
Signal Word Danger
Symbol GHS07, GHS08
Hazard Declaration H302; H350
Caution Statement P201; P308 + P313

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Product Style

_MG_4749

 

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Thanks for your considering of Hebei Shuoxi Biotechnology Co., Ltd.(HBSX).   HBSX is a fast growing intermediates company,Which located in Shijiazhuang,Hebei Province.
HBSX is specialized in pharmaceutical intermediates, veterinary drug intermediates and dyes intermediates,such as phenylacetamide, dimethylamine hcl, benzyl chloride etc., HBSX also supply various industrial chemicals for customers, such as citric acid,potassium chloride etc.
After ten years development,HBSX has become a Diversified development company,not only involves in chemicals, but also real estate ,clothes ,agricultural products and so on.
So far, HBSX has business in more than 35 countries,most big customers come from europe and America, because among the suppliers in china,HBSX can always make the product quality best, some of the products from HBSX can reach the purity of 99.9+, such as 2-phenylacetamide. This is the important reason for customers who choosing HBSX.
In future, HBSX must become to a more important trade bridge for china and foreign countries especially in pharmaceutical industries.

 

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Why Choose US?
1. Selecting raw materials strictly,our products are the highest purity.
2.Reasonable and competitive price. Provide the best and professional service.
3.Fast delivery of the samples ,samples from stock. Reliable shipping way.
4.Full experience of large numbers containers loading in Chinese sea port.
5. Best after-service after shipment .
6. Professional documents for your custom clearance.

 

FAQ:
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.

Q2:What’s your MOQ?
A: For the high value product, our MOQ starts from 10g,100g and 1kg.

Q3:Which kind of payment terms do you accept?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment
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Q4:How about your delivery time?
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Q5:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.


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