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Tetracaine hydrochloride crystalline CAS:136-47-0

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Description
Tetracaine (also known as amethocaine) is a local anesthetic of the ester anesthetic group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
Tetracaine is the T in TAC, a mixture of 5 to 12 per cent tetracaine, 0.05 per cent adrenaline, and 4 or 10 per cent cocaine hydrochloride used in ear, nose & throat surgery and in the emergency department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
It is on the World Health Organization’s List of Essential Medicines, a list of the most important medication needed in a basic health system.
A systematic review investigated tetracaine for use in emergency departments, especially for IV cannulation in children, in view of its analgesic and cost-saving properties. However, it did not find an improvement in first attempt cannulations.

Basic Info

Chemical Name Tetracaine hydrochloride
Synonyms tonexol;Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester, monohydrochloride;PANTOCAINE;4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester,Amethocaine hydrochloride;anethaine;Expand
CAS No. 136-47-0
Molecular Formula C15H25ClN2O2
Molecular Weight 300.82400
PSA 41.57000
LogP 3.49200

 

Numbering system

RTECS number DG4900000
PubChem number 24277740
EINECS number 205-248-5
MDL number MFCD00038912

 

Properties

Appearance & Physical State White or off white crystalline powder
Boiling Point 389.4ºC at 760 mmHg
Melting Point 149ºC
Flash Point 189.3ºC
Stability Stable at normal temperatures and pressures.
Storage Condition Keep tightly closed.
Vapor Pressure 2.87E-06mmHg at 25°C

 

Safety Info

RTECS DG4900000
Hazard Class 6.1
Safety Statements S26-S36/37-S45
HS Code 2942000000
Packing Group III
RIDADR UN 2811
Risk Statements R25; R36; R43
Hazard Codes T

 

Contact Us
wechat/whatsapp +8613081092107
skype/e-mail julia@hbshuoxi.com

 

Product Style

_MG_4740

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Company Products And Packaging

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Thanks for your considering of Hebei Shuoxi Biotechnology Co., Ltd.(HBSX).   HBSX is a fast growing intermediates company,Which located in Shijiazhuang,Hebei Province.
HBSX is specialized in pharmaceutical intermediates, veterinary drug intermediates and dyes intermediates,such as phenylacetamide, dimethylamine hcl, benzyl chloride etc., HBSX also supply various industrial chemicals for customers, such as citric acid,potassium chloride etc.
After ten years development,HBSX has become a Diversified development company,not only involves in chemicals, but also real estate ,clothes ,agricultural products and so on.
So far, HBSX has business in more than 35 countries,most big customers come from europe and America, because among the suppliers in china,HBSX can always make the product quality best, some of the products from HBSX can reach the purity of 99.9+, such as 2-phenylacetamide. This is the important reason for customers who choosing HBSX.
In future, HBSX must become to a more important trade bridge for china and foreign countries especially in pharmaceutical industries.

 

Packing

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Why Choose US?
1. Selecting raw materials strictly,our products are the highest purity.
2.Reasonable and competitive price. Provide the best and professional service.
3.Fast delivery of the samples ,samples from stock. Reliable shipping way.
4.Full experience of large numbers containers loading in Chinese sea port.
5. Best after-service after shipment .
6. Professional documents for your custom clearance.

 

FAQ:
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.

Q2:What’s your MOQ?
A: For the high value product, our MOQ starts from 10g,100g and 1kg.

Q3:Which kind of payment terms do you accept?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment
by T/T, Western Union or Alibaba). Bulk order by T/T or L/C.

Q4:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.

Q5:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.


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